Rodrigo B. Andrade

 

andrade

Associate Professor

B.A. (1996), Johns Hopkins University
Ph.D. (2001), Massachusetts Institute of Technology
NIH Postdoctoral Fellow (2003-2005), University of Texas at Austin

OFFICE
Beury Hall 452


MAILING ADDRESS

Department of Chemistry
Beury Hall 130
1901 N. 13th Street
Philadelphia, PA 19122


PHONE

office: 215-204-7155
fax: 215-204-9851

lab: 215-204-3423

E-MAIL
randrade@temple.edu


RESEARCH GROUP

http://chem.cst.temple.edu/~randrade/

Medicinial / Organic

Research Interests

    We are interested in the following general areas of Organic Chemistry:

  • Total Synthesis of Bioactive Natural Products and Analogs Thereof
  • Synthetic Methodology
  • Carbohydrate Chemistry (Methodology, Synthesis)
  • Development of Carbohydrate Based Drugs and Vaccines

 

Selected Publications

 

Yu, Arthur; Shang, Jing; Cheng, Fang; Paik, Bradford A.; Kaplan, Justin M.; Andrade, Rodrigo B.; Ratner, Daniel M. "Biofunctional Paper via the Covalent Modification of Cellulose" Langmuir (2012), 28, 30, 11265 - 11273

 

Velvadapu, V.; Glassford, I.; Lee, M.; Paul, T.; Debrosse, C.; Klepacki, D.; Small, MC.; Mackerell, AD Jr.; Andrade RB. "Desmethyl Macrolides: Synthesis and Evaluation of 4, 10-Didesmethyl Telithromycin" ACS Medicinal Chemistry Letters (2012), 3, 3, 211 - 215

 

Velvadapu, Venkat; Paul, Tapas; Wagh, Bharat; Andrade, Rodrigo B.; "Total Synthesis of (-)-4,8,10-Tridesmethyl Telithromycin "Journal of Organic Chemistry (2011), 76, 18, 7516-7527

 

Sirasani, Gopal; Andrade, Rodrigo B.; "Total Synthesis of (-)-Leuconicine A and B" Organic Letters (2011), 13, 17, 4736-4737

 

Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B.; "Sequencing cross-metathesis and non-metathesis reactions to rapidly access building blocks for synthesis" Tetrahedron (2011), 67, 12, 2197-2205

 

Velvadapu, Venkat; Paul, Tapas; Wagh, Bharat; Andrade, Rodrigo B.; "Desmethyl Macrolides: Synthesis and Evaluation of 4,8, 10=Tridesmethyl Telithromycin" ACS Medicinal Chemistry Letters (2011), 2, 1, 68-72

 

Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B.; "Total Synthesis of (+)-crocacin C" Bioorganic & Medicinal Chemistry. (2010), 3648-3688

 

Sirasani, Gopal; Paul, Tapas; Dougherty, William Jr.; Kassel, Scott; Andrade, Rodrigo B.; "Concise Total Syntheses of (+-)-Strychnine and (+-)-Akuammicine" Journal of Organic Chemistry (2010), 75, 3529-3532

 

Andrade, R.B.; "Syntheses of the Crocacins. A Review." Organic Preparations. (2009), 41, 359-383

 

Sirasani, Gopal; Andrade, Rodrigo B.; "Sequential One-Pot Cyclizations: Concise Access to the ABCE Tetracyclic Framework of Strychnos Alkaloids" Organic Letters. (2009), 11, 10, 2085-2088

 

Fortin, Michael; Kaplan, Justin; Pham, Khoa; Kirk, Sharon; Andrade, Rodrigo B.; "gem-Dimethyl 4-Pentenyl Glycosides: Novel Glycosylating Agents and Anomeric Protecting Groups" Organic Letters. (2009), 11, 16, 3594-3597

 

Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B.; "Concise Total Synthesis of (+)-crocacin C" Journal of Organic Chemistry. (2008), 73, 6386-6388

 

Andrade, R. B. “Key Strategies in Glycan Synthesis” Wiley Encyclopedia of Chemical Biology. (2008), 1-12.


Velvadapu, V.; Andrade, R. B. “Concise Syntheses of D-Desosamine, 2-Thiopyrimidinyl Desosamine Donors and Methyl Desosaminide Analogues from D-Glucose.” Carb. Res., (2008), 343, 145-150.