Rodrigo B. Andrade

 

andrade

Associate Professor

B.A. (1996), Johns Hopkins University
Ph.D. (2001), Massachusetts Institute of Technology
NIH Postdoctoral Fellow (2003-2005), University of Texas at Austin

OFFICE
Beury Hall 452


MAILING ADDRESS

Department of Chemistry
Beury Hall 130
1901 N. 13th Street
Philadelphia, PA 19122


PHONE

office: 215-204-7155
fax: 215-204-9851

lab: 215-204-3423

E-MAIL
randrade@temple.edu


RESEARCH GROUP

http://chem.cst.temple.edu/~randrade/

Medicinial / Organic

Research Interests

    We are interested in the following general areas of Organic Chemistry:

  • Total Synthesis of Bioactive Natural Products and Analogs Thereof
  • Synthetic Methodology
  • Carbohydrate Chemistry (Methodology, Synthesis)
  • Development of Carbohydrate Based Drugs and Vaccines

 

Selected Publications

Wagh, Bharat; Paul Tapas; DeBrosse, Charles; Andrade, Rodrigo B. et al. "Desmethyl Macrolides: Synthesis and Evaluation of 4,8,10-Tridesmethyl Cethromycin" ACS Medicinal Chemistry Letters (2013), 4, 11, 1114-1118

 

Zhao, Senzhi; Sirasani, Gopal; Vaddypally, Shivaiah; Andrade, Rodrigo B. et al. "Total Synethsis of (-)-Melotenine A" Angewandte Chemie-International Edition (2013), 52, 32, 8309-8311

 

Kaplan, Justin M.; Shang, Jing; Gobbo, Pierangelo; Andrade, Rodrigo B. et al. "Conformationally Constrained Functional Peptide Monolayers for the Controlled Display of Bioactiv Carbohydrate Ligands" Langmuir (2013), 29, 26, 8187-8192

 

Small, Meagen C.; Lopes, Pedro; Andrade, Rodrigo B.; et al. "Impact of Ribosomal Modification on the Binding of the Antibiotic Telithromycin Using a Combined Grand Canonical Monte Carlo/Molecular Dynamics Simulation Approach" Plos Computational Biology (2013), 9, 6, e1003113

 

Wagh, Bharat; Paul Tapas; Glassford, Ian; Andrade, Rodrigo B.; et al. "Desmethyl Macrolides: Synthesis and Evaluation of 4,8-Didesmethyl Telithromycin" ACS Medicinal Chemistry Letters (2012), 3, 12, 1013-1018

 

Yu, Arthur; Shang, Jing; Cheng, Fang; Paik, Bradford A.; Kaplan, Justin M.; Andrade, Rodrigo B.; Ratner, Daniel M. "Biofunctional Paper via the Covalent Modification of Cellulose" Langmuir (2012), 28, 30, 11265 - 11273

 

Velvadapu, V.; Glassford, I.; Lee, M.; Paul, T.; Debrosse, C.; Klepacki, D.; Small, MC.; Mackerell, AD Jr.; Andrade RB. "Desmethyl Macrolides: Synthesis and Evaluation of 4, 8-Didesmethyl Telithromycin" ACS Medicinal Chemistry Letters (2012), 3, 3, 211 - 215

 

Velvadapu, Venkat; Paul, Tapas; Wagh, Bharat; Andrade, Rodrigo B.; "Total Synthesis of (-)-4,8,10-Tridesmethyl Telithromycin "Journal of Organic Chemistry (2011), 76, 18, 7516-7527

 

Sirasani, Gopal; Andrade, Rodrigo B.; "Total Synthesis of (-)-Leuconicine A and B" Organic Letters (2011), 13, 17, 4736-4737

 

Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B.; "Sequencing cross-metathesis and non-metathesis reactions to rapidly access building blocks for synthesis" Tetrahedron (2011), 67, 12, 2197-2205

 

Velvadapu, Venkat; Paul, Tapas; Wagh, Bharat; Andrade, Rodrigo B.; "Desmethyl Macrolides: Synthesis and Evaluation of 4,8-Tridesmethyl Telithromycin" ACS Medicinal Chemistry Letters (2011), 2, 1, 68-72

 

Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B.; "Total Synthesis of (+)-crocacin C" Bioorganic & Medicinal Chemistry. (2010), 3648-3688

 

Sirasani, Gopal; Paul, Tapas; Dougherty, William Jr.; Kassel, Scott; Andrade, Rodrigo B.; "Concise Total Syntheses of (+-)-Strychnine and (+-)-Akuammicine" Journal of Organic Chemistry (2010), 75, 3529-3532