David R. Dalton


David Dalton


B.A.(1957), Northwestern University
Ph.D. (1962) University of California,Los Angeles
Postdoctoral Fellow ('64-65) Ohio StateUniversity


BeuryHall 342

Department of Chemistry
Beury Hall 130
1901 N. 13th Street
Philadelphia, PA 19122

office: 215-204-7138
fax: 215-204-1532
lab: 215-204-7146, -7149





Research Interests


Synthetic and Mechanistic Organic Chemistry

Syntheses of materials related to 14-hydroxydihydrocodeinone are being explored.

Gas phase kinetics, both experimental and theoretical (DFT) exploring the formation of imines is underway.


Note...methyl amines can be substituted for waters.

Selected Publications


Judge, E; Brady, J; Dalton, D; "Analysis of Pharmaceutical Compounds from Glass, Fabric, Steell and Wood Surfaces at Atmospheric Pressure Using Spatially Resolved, Nonresonant Femtosecond Laser Vaporization Electrospray Mass Spectrometry." Analytical Chemistry. (2010) 82, 8, 3231-3238.


Mascavage, LM; Tierney, J; Sonnet, PE; Dalton, D; "The Hoffmann-Schiff dichotomoy: on the reaction between chloral and amines." Arkivoc. (2010) 8, 278-284.


Mascavage, LM; Zhang-Plasket, F; Sonnet, PE; "Gas phase surface-catalyzed HCl addition to vinylacetylene: motion along a catalytic surface. Experiment and theory". Tetrahedron. (2008) 40, 64, 9357-9367.


P. E. Sonnet, L. M. Mascavage, D. R. Dalton, "The first steps: The attack on the carbonyl carbon of pyridoxal cofactor in pyridoxal-dependent enzymes".  Bioorganic & Medical Chemistry Letters. (2008) 18, 744-748.


L. M. Mascavage, P. E. Sonnet, D. R. Dalton, "On the surface-catalyzed reaction between the gases 2,2-dimethylpropanal and methanamine". J. Org. Chem. (2006) 71, 3435-3443.

L. M. Mascavage, M. L. Wilson, D. R. Dalton, "Syntheses of morphine and codeine (1992-2002): Templates for exploration of synthetic tools". Current Organic Synthesis. (2006) 3, 99-120.

M. L. Wilson, D. R. Dalton, P.J. Carroll, "Decoration of the Aromatic Ring of Dihydrocodeinone (Hydrocodone) and 14-Hydroxydihydrocodeinone (Oxycodone)". J. Org. Chem. (2005), 70, 6492.