Our group is focused on developing new synthetic methodologies to tackle challenges in organic synthesis and in biological systems. Our main efforts will be to develop novel biocatalysts and transition metal catalysts for applications in the pharmaceutical industry, petroleum industry, and to other fine chemicals such as fragrances, agrochemicals, and small molecule synthesis.
We aim to take advantage of the unique reactivity of these catalysts in order to address challenges in chemical synthesis. We work at the interface of biological, inorganic, and organic chemistry to design and understand how our catalysts work.
Beryl X. Li*, Daniel K. Kim*, Steven Bloom, Richard Y.-C. Huang, Jennifer X. Qiao, William R. Ewing , Daniel G. Oblinsky, Gregory D. Scholes, and David W. C. MacMillan. Site-selective tyrosine bioconjugation via photoredox catalysis for native-to-bioorthogonal protein transformation. Nature Chemistry, 2021. *Co-First Author
Daniel K. Kim, Jan Riedel, Raphael S. Kim, and Vy M. Dong. Cobalt Catalysis for Enantioselective Cyclobutanone Construction. J. Am. Chem. Soc. 2017, 139, 30, 10208–10211.
Jung-Woo Park, Kevin G. M. Kou, Daniel K. Kim, and Vy M. Dong. Rh-catalyzed desymmetrization of α-quaternary centers by isomerization-hydroacylation. Chem. Sci., 2015, 6, 4479–4483.
Qing-An Chen, Daniel K. Kim, and Vy M. Dong. Regioselective Hydroacylation of 1,3-Dienes by Cobalt Catalysis. J. Am. Chem. Soc. 2014, 136, 10, 3772–3775.
Timothy W. Funk, Andrew R. Mahoney, Rebecca A. Sponenburg, Kathryn P. Zimmerman, Daniel K. Kim, and Emily E. Harrison. Synthesis and Catalytic Activity of (3,4-Diphenylcyclopentadienone)Iron Tricarbonyl Compounds in Transfer Hydrogenations and Dehydrogenations. Organometallics 2018, 37, 7, 1133–1140.
Taylor N. Plank, Jessica L. Drake, Daniel K. Kim, and Timothy W. Funk. Air‐Stable, Nitrile‐Ligated (Cyclopentadienone)iron Dicarbonyl Compounds as Transfer Reduction and Oxidation Catalysts. Adv. Synth. Catal. 2012, 354, 597–601.