Temple University Department of Chemistry
  • Home
  • Faculty
  • Research
    • Research Faculty
    • Research Institutes
    • Facilities
  • Graduate
    • Apply
    • Program requirements
    • Course offerings
    • Professional Science Masters in Forensic Chemistry
    • Student life
    • Fellowship opportunities
  • Undergraduate
    • Program overview
    • Undergraduate research
    • TU Chemistry Society (TUCS)
    • Scholarship opportunities
  • Alumni
  • Resources
    • Safety
    • Strengthening Climate
    • Syllabi
    • Book an instrument
    • Ombudsperson
    • Machine shop
    • Library
    • Software
  • Contact
    • Staff
    • TU directory
Picture
Picture
Picture
Picture
Picture
Specialties
Picture
Picture
Picture
Picture
Picture
Picture
Picture
Picture
Picture
Picture
Picture

Robert Stanley

Professor
Biophysical,  Biochemistry, Physical
Office: Beury 250B
Phone: 215-204-2027
Send an email
​Visit website

Biography

1991-1996

1991

1978
Postdoctoral researcher, Stanford University

Ph.D. Pennsylvania State University

B.S. University of California, Berkeley

Interests

DNA is often damaged by UV radiation penetrating the ozone layer. The Stanley group uses ultrafast laser spectroscopy and biochemistry to understand the mechanism of DNA repair by DNA photolyase. Photolyase is a flavoprotein that uses light to drive an photoinduced electron transfer reaction repairing the bound DNA lesion. We are using ultrafast laser and biochemical techniques to unravel the substrate binding and repair mechanism. 

​We are also interested in how the redox properties of flavoenzymes are tuned by the protein binding site. We are studying these interactions quantitatively using Stark spectroscopy.

Select Publications

Stanley, R. J. & van Galen, C. J. in Methods Enzymol. Vol. 620 New Approaches for Flavoenzyme Catalysis (ed Bruce A. Palfey)  215-250 (Elsevier, 2019).

Bialas, C. et al. Ultrafast flavin/tryptophan radical pair kinetics in a magnetically sensitive artificial protein. PCCP 21, 13453-13461, doi:10.1039/c9cp01916b (2019).

Rousseau, B. J. G., Shafei, S., Migliore, A., Stanley, R. J. & Beratan, D. N. Determinants of Photolyase's DNA Repair Mechanism in Mesophiles and Extremophiles. J. Am. Chem. Soc. 140, 2853-2861, doi:10.1021/jacs.7b11926 (2018).

Rohwer, E. J. et al. Dipole Moment and Polarizability of Tunable Intramolecular Charge Transfer States in Heterocyclic pi-Conjugated Molecular Dyads Determined by Computational and Stark Spectroscopic Study. Journal of Physical Chemistry C 122, 9346-9355, doi:10.1021/acs.jpcc.8b02268 (2018).

Munshi, S., Rajamoorthi, A. & Stanley, R. J. Characterization of a cold-adapted DNA photolyase from C-psychrerythraea 34H. Extremophiles 21, 919-932, doi:10.1007/s00792-017-0953-z (2017).

TEMPLE UNIVERSITY
COLLEGE OF SCIENCE AND TECHNOLOGY
DEPARTMENT OF chemistry

Department of Chemistry
Temple University
1901 N. 13th St.
Philadelphia, PA 19122-6081
Temple University Cherry and White Directory
Contact
TEMPLE
CST
TUPORTAL
TUMAIL
ACCESSIBILITY
POLICIES
CAREERS
Copyright 2015. Temple University. All rights reserved.