Our research in bioinorganic chemistry focuses on biologically relevant metals that are very sensitive to hydrolysis – mainly iron and titanium – and addresses how biology handles these difficult metals. Problems relate to metal uptake and transport, potential therapeutic applications thereof, and biomineralization.
Contemplating a Role for Titanium in Organisms
MR Zierden, AM Valentine
Metallomics 2016, 8, 9-16.
Titanium Mineralization in Ferritin: A Room Temperature Non-Photochemical Preparation and Biophysical Characterization
FF Amos, KE Cole, RL Meserole, JP Gaffney, AM Valentine
J. Biol. Inorg. Chem. 2013, 18, 145-152.
Titanium(IV) and Vitamin C: Aqueous Complexes of a Bioactive Form of Ti(IV)
KM Buettner, JM Collins, AM Valentine
Inorg. Chem. 2012, 51, 11030-11039.
The Challenges of Trafficking Hydrolysis Prone Metals and Ascidians as an Archetype
JP Gaffney, AM Valentine
Dalton Transactions 2011, 40, 5827-5835.