Specialties

Sarah Wengryniuk

Associate Professor
​Robert L. Smith Early Career Professor
Organic

Office: Beury 442
Phone: 215-204-0360
Send an email
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Biography

2012-2015

2012

2007

Selected Awards

Postdoctoral researcher, Scripps Research Institute

Ph.D. Duke University

B.S. Winthrop University

Robert L. Smith Early Career Professor.  NSF CAREER Award.  Italia-Eire Foundation Distinguished Teacher of the Year.  NIH Ruth L. Kirchstein NRSA F32 Postdoctoral Fellowship. National Science Foundation Graduate Research Fellowship. Merck Inc. Women In Chemistry Fellowship.

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Interests

Our lab aims to develop a multifaceted research program focusing on asymmetric methods development and natural product synthesis as the means for fueling biological investigations. Our research program will provide students with training across multiple scientific fields and aid in their understanding of the interplay between chemistry and biology.  Representative research areas include C–H activation, asymmetric C–C bond formation, novel methods to access carbon, oxygen, and nitrogen containing ring systems, and the synthesis of natural products targeting cancer metastasis.

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Select Publications

Sousa e Silva, F. C., Van, N. T., Wengryniuk, S. E. Direct C–H Alpha-Arylation of Enones with ArI(O2CR)2 Reagents. J. Am. Chem. Soc. 2020, 142, 1, 64.

Xiao, X., Greenwood, N. S., Wengryniuk, S. E. Dearomatization of Electron-Deficient Phenols to ortho-Quinones Enabled by Bidentate Nitrogen-Ligated I(V) Reagents. Angew. Chem. Int. Ed. 2019, 58, 16181-16187.

Mikhael, M., Adler, S. A., Wengryniuk, S. E. Chemoselective Oxidation of Equatorial Alcohols with N-Ligated Lambda-3 Iodanes. Org. Lett, 2019, 21, 5889–5893. 
 
Walters, J. C., Tierno, A. F., Dubin, A. H., Wengryniuk, S. E. (Poly)cationic lambda3-Iodane Mediated Oxidative Ring Expansion of Secondary Alcohols. Eur. J. Org. Chem. 2018, 1460-1464.